Prevention of the disease to cure. Mainly lies in prevention of perinatal asphyxia of cattle, we must continue to improve the obstetric techniques, the timely processing of fetal distress, and the end of maternity leave as soon as possible. The Inflatable Obstacles baby after birth asphyxia recovery in a timely manner, so as to reduce the occurrence of HIE.
Generally believed that, if a comprehensive recovery measures, and save 20 minutes still not resumed breathing independently or Apgar score is still lower than 1 minute, the brain has been serious irreversible damage.
(A) general treatment
Keep quiet, oxygen, warmth, and maintain airway patency. Correct acidosis. A coagulation disorder, can be given vitamin K1 5mg / d, or lose blood or plasma. Timely correction of low blood sugar, such as hypocalcemia.
(B) Intensive Care
For cardiopulmonary, blood pressure, intracranial pressure and EEG monitoring and strict observation of body temperature, breathing, thought, eyes Chong, pupil size, the former on existing early convulsions, and whether or not the situation. And the maintenance of blood pH in the normal range. When there is shock and cardiac dysfunction should be promptly dealt with.
(C) the maintenance of heat and appropriate amount of fluid restrictions
General health after three days of the liquid Inflatable Obstacles volume should be limited to 60 to 80 per mouth ml / kg per hour infusion rate of 4 ml / kg. Glucose daily intake of 10 to 20 g / kg, the blood sugar remained at 4.2 to 5.6 mmol / L, when necessary, to high intravenous nutrition. Cautiously uses sodium bicarbonate should be increased so as to avoid cerebral edema.
(4) anticonvulsant therapy
The treatment of neonatal convulsions HIE First of all, pay attention to the possible existence of metabolic disorders such as hypoglycemia, hypocalcemia and hypomagnesemia, hyponatremia, etc. dealt with immediately. Once the seizure is not determined by the metabolic disorder caused preparing anticonvulsant drugs. In principle, to choose a drug dose should be adequate, or either of the two drugs used interchangeably. Drug use during regular monitoring of blood concentration, after close observation of medication to stop seizures, quiet sleep, respiratory rhythm steady, fortune means bending a certain degree of tension.
1. Phenobarbital
Control of neonatal convulsions preferred. Giving first load of 15 ~ 20 mg / kg, slow intramuscular injection or intravenous injection. If not yet control seizures, every 10 to 15 minutes to give 5 mg / kg, until the seizures stop, volume up to 30 mg / kg, respectively. Convulsion control after 12 to 24 hours of maintenance to the beginning of the day at 5 mg / kg, a two intramuscular or intravenous injection every 12 hours, 1, 2 to 3 days after oral administration to maintain. Noting combined with the stability of the respiratory depression.
2. Stability
For the treatment of neonatal convulsions
Inflatable Obstacles status of preferred drugs for each dose of 0.3 to 0.5 mg / kg, slow intravenous injection. The drug half-life of 15 minutes, through the blood-brain barrier quickly, it is almost disappear, it may be 15 to 20 minutes so after repeated use, can be used within a day three to four times. Difficult to control the cut-off day when the seizures to be 3 to 12 mg / kg continuous intravenous infusion.